A number of docs ET spoke to mentioned ICMR‘s determination to not embrace the drug creates confusion, and questioned what the medical analysis physique was doing when the drug was permitted for restricted emergency use by the Drug Controller Normal of India (DCGI).
“It has positively created loads of confusion,” mentioned Vasant Nagvekar, an infectious ailments specialist at Mumbai-based Lilavati Hospital and member of the Maharashtra authorities’s Covid-19 activity pressure.
Nagvekar mentioned as per the Maharashtra authorities protocol the drug could also be thought of for individuals above 65 and people who are at excessive threat for progressing to extreme illness. “We do not have particular therapies for these teams,” Nagvekar mentioned.
“Molnupiraivir could have a job in people at a excessive threat of degradation, particularly if unvaccinated,” mentioned Lancelot Pinto, advisor pulmonologist and epidemiologist at Mumbai-based PD Hinduja Hospital.
Nonetheless, Pinto mentioned ICMR’s transfer to not embrace the molnupiravir is prone to do extra good than hurt, as medicine meant to be used in a really particular subset of the inhabitants could typically find yourself getting used indiscriminately in India.
“It seems that each different division is working in silos. The ICMR ought to have had a phrase with CDSCO/DCGI earlier than the (molnupiravir) approval,” mentioned Satyanarayana Mysore, HOD & advisor, pulmonology and lung transplant doctor at Manipal Hospitals in Bangalore.
Mysore says (Balram) Barghava’s (DG, ICMR) touch upon the potential indiscriminate use of the antiviral is an “insult” to clinicians.
“At this level within the pandemic, I really feel it is too untimely to discard this drug until a well-conducted detrimental examine comes by means of. Extra so as a result of there are only a few medicine in our arsenal towards the Covid-19 struggle,” mentioned Sanjith Saseedharan, advisor & head, essential care at SL Raheja Hospital.
Swati Rajagopal, infectious illness specialist at Aster CMI Hospital in Bangalore, says that the security of the drug is set by DCGI and the rationale for not together with it within the nationwide guideline on grounds of security does not appear proper.